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Muriel was born in Seattle, spent a few crazy years in Chicago and now lives in Los Angeles.

She studied at Seattle University, iO Chicago, Second City Chicago, UCB LA, The Ruby LA, and The Groundlings.

She cohosts the Podcast Hella In Your Thirties with her husband Nick Casalini.

She and Nick also created-wrote-starred-in-edited-everything-else the web series Fam Club about Drake's nerdy brother and sister.